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This article also reviewed network pharmacology analyses published previously to identify and explore the potential molecular targets of Rg1 in PD treatment, while evaluating strategies such as drug delivery technologies, optimizing administration routes, and combination therapies

Key pathways influenced include PI3K/Akt and MAPK, which control protein synthesis, nutrient utilization, and cell division

Indeed, this resulted in a decrease in pro-inflammatory cytokines and reduced expression of the innate immune protein, toll-like receptor 4 (TLR4), and H 1 and H 4 receptors on the microglia

Statements Author contributions SR: Conceptualization, Writing original draft, Writing review & editing

Yasui, F