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Many drugs used to treat obesity in the past have been discontinued because of their potential to be abused and their toxicities [20-27] (Table 1 )

Inborn errors of cobalamin absorption and metabolism

AOD 9604 is an unlicensed synthetic hGH peptide fragment with limited human trial data, while retatrutide is an investigational triple incretin receptor agonist

Lipotropic injections are a great addition to a healthy diet

Less frequently, patients present with isolated perianal complaints, upper gastrointestinal disease, or extra intestinal manifestations (EIMs), which can affect the skin, joints, eyes, liver, blood vessels, and kidneys

While the potential of tripeptides in biomedical applications has been proven significant, challenges such as stability, bioavailability, and immunogenicity need to be addressed