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This led to additional trials which proved to be unsuccessful [125]

Liver Core Biopsy Findings Low power shows minimal nonspecific mononuclear inflammation predominantly in the periportal area

cancer cells with high FSP1 expression often exhibit stronger resistance to GPX4 inhibitors (125)

However, for a cell, having parallel pathways is important because, if a mutation occurs in selenocysteine lyase, for example, selenoprotein production will halt, making the cell more susceptible to ferroptosis, explained Alex Inague, co-first author of the study

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