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Nature 437, 759763

23, 27 Vitamin B 12 Early treatment of B 12 deficiency is particularly important because neurologic symptoms may be irreversible

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Safety, Tolerability, and Regulatory Perspective Multiple non-clinical toxicology programs and clinical studies have evaluated the safety of AOD 9604: A comprehensive non-clinical dossier reported no evidence of genotoxicity or major toxicological concerns across a range of pharmacokinetic and toxicity studies, supporting a favorable safety profile in standard preclinical models

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In the human clinical trial, the trajectory of weight loss became apparent during this window