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Hofman A

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doi: 10.1016/j.ecoenv.2021.112286

The non-compartmental model was chosen to perform the pharmacokinetic analysis

This approach may be especially favorable when difficult to replace cells, like neurons in the brain, become senescent

In vivo studies have confirmed that DSF and Cu have synergistic effects with TMZ and improve survival in mice with in situ GBM tumors (Lun et al., 2016)