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Although low vitamin B12 levels did not have a significant predictive value for EDS, there was a significant correlation between low vitamin B12 levels and EDS in obese patients (BMI 30) (OR = 3.996, 95% CI = 1.00615.876, p = 0.039)

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This guide explains why the risk arises, how to recognise symptoms, what monitoring is recommended on the NHS, and which supplementation options are available, helping patients and clinicians manage this preventable but potentially irreversible condition effectively

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Occasionally, a bone marrow biopsy is done to help confirm the diagnosis

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levamisole (alkaline phosphatase inhibitor), and dipyridamole (DYP, nucleoside transporter inhibitor)

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