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[DOI] [PMC free article] [PubMed] [Google Scholar] 9.Autism and Developmental Disabilities Monitoring Network Surveillance Year 2006 Principal Investigators

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TMAO activated the expression of the inflammatory mediator high mobility group box 1 (HMGB1), which stimulated multiple receptors such as toll-like receptor 4 (TLR4), thus mediating extracellular signal-regulated kinases 1 and 2 (ERK1 and ERK2) and the NF-B signaling pathway (82)

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