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2022 doi: 10.21203/rs.3.rs-1186638/v1

The clinical pharmacology of 6-mercaptopurine

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1c emphasises APX-dependent removal of H 2 O 2 , other ROS such as superoxide may also chemically oxidize both ascorbate and glutathione (Polle 2001)

Cell Host Microbe 4, 2839

The GSH moiety of the drug has to be processed by GT before further processing by dipeptidases to generate dimethylarsino-cysteine (DMAC), a cysteine S -conjugate which is imported via cystine transporters ( Figure 4 )
