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15 identified a critical role for Ca 2+ /calmodulin kinase II-positive neurons in the dorsal cochlear nucleus in sustaining tinnitus perception in mice with noise-induced tinnitus, despite the absence of permanent hearing loss

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Given that targeted genetic therapies are primarily applicable to the minority fALS cases, a major strategic imperative is to develop interventions for the overarching pathological processes common to both fALS and sALS

doi: 10.2337/diacare.26.7.2139 158

Tmax, Time to reach maximum plasma concentration