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The PGD gene is located on chromosome 1p36.33 and is composed of 13 exons that generate three alternatively spliced mRNAs, each of which encode different sized protein isoforms
This imbalance plays a significant role in aging, cancer, cardiovascular diseases, and neurodegenerative disorders
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I.ReitmayerC.ArndtC.WoberJ.KretzschmarG.ZierauO.et al (2012)
Siber GR, Gorham C, Durbin W, Lesko L, Levin MJ
Advanced approaches like gene therapy and stem cell therapy are invasive, expensive, and time-consuming thus limiting their application in sciatic nerve injury
