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Acetyl-L-carnitine provides effective in vivo neuroprotection over 3,4-methylenedioximethamphetamine-induced mitochondrial neurotoxicity in the adolescent rat brain

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Importantly, in these experimental models, pre-hypoxic treatment with sodium 2-[5-(4-chlorophenyl)-pentyl]-oxirane-2-carboxylate (POCA) or oxfenicine, both inhibitors of CPT I, prevents membrane and cytosolic LCAC accumulation in early ischaemia and the genesis of electrophysiological derangements (Yamada et al., 1994)

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2.Compliance with the standards for food and drug