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Multidrug resistance proteins (MRPs, ABCCs): Importance for pathophysiology and drug therapy

Clark CCT, Taghizadeh M, Nahavandi M, Jafarnejad S

They discovered that peroxisome proliferator-activated receptor-g (PPAR/G) signaling was suppressed, while the fatty acid import by fatty acid transport protein 1 (FATP1) was activated, thus triggering fatty acid accumulation in BaP exposed BEAS-2B cells, and the above changes were abolished by resveratrol intervention

Research published in Brain Communications highlights that those with Alzheimers disease and mild cognitive impairment often show reduced levels of glutathione in critical brain areas, like the left hippocampus

Circ Res 2005

2023;13 doi: 10.1038/s41598-023-37333-4