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Jhun BS, Mishra J, Monaco S, Fu D, Jiang W, Sheu SS, et al

In the overall analysis of IC 50 sensitivity versus differentiation state, we combined p values by first adapting Browns method, a more conservative extension of Fishers method, to account for reduced independence of testing the same cell lines using different inhibitors (Poole et al., 2016)

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Apply once per day and increase to twice a day if well tolerated

placebo) [3]