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2 Targeting iron ions and ROS to induce ferroptosis Studies have shown that various traditional Chinese medicines such as artemisinin and artemisinin can induce ferroptosis by increasing ROS content, thereby affecting iron metabolism, exerting anti-liver cancer effects and low toxicity, and are very promising drugs[9]

Petta V, Gkiozos I, Strimpakos A, Syrigos K

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2019;186:132 Ethics declarations Conflict of interest The authors declare no competing interests

Determination of catalase activity: Cell catalase activity was determined using a microplate reader (BioTek Synergy HT) at 240 nm as described by Aebi (1984)