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However, new approaches, concurrent with the development of sophisticated bioinformatic and genomic tools, are being used to explore peptide-based therapeutics to manipulate endogenous pathways and targets, including undruggable intracellular protein-protein interactions (PPIs)

ChemBioChem 12:3842 Tyagi A, Tuknait A, Anand P, Gupta S, Sharma M, Mathur D, Joshi A, Singh S, Gautam A et al (2015) CancerPPD: a database of anticancer peptides and proteins

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IGF-1 LR3 (Insulin-like Growth Factor-1 Long Arg) is a synthetic analog of IGF-1 that directly activates cellular growth, repair, and recovery pathways while offering greater stability and potency than natural IGF-1
