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Pathway network of pyroptosis and its potential inhibitors in acute kidney injury

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The experimental findings demonstrated that grape seed PCs inhibited the activation and nuclear translocation of NF-kB while downregulating the expression of proinflammatory cytokines such as TNF- , IL-1, and IL-6, as well as cyclooxygenase-2

Oral aspirin and ibuprofen increase cytokine-induced synthesis of IL-1 beta and of tumour necrosis factor-alpha ex vivo

Compared to control cells (set as 100%), pre(adipocytes) incubated with 1% lotus leaf extract solution displayed a decrease in ADD1/SREBP-1c mRNA levels over time