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Zucca et al., 2014), which in turn decomposes to resting-state upon reaction with a second hydrogen peroxide molecule (reaction 5): A NADPH molecule is bound to each subunit, minimizing H 2 O 2 mediated inactivation [105]

PMID: 12 Al-DhabiN

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Besides, it stimulated expression of early growth response 1 (egr-1) gene responsible for cytokine and growth factor generation and early extracellular matrix (collagen) formation (but also its repressor nerve growth factor 1-A binding protein-2 (nab2)) (44)

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At predetermined (0, 5, 10, 15, 20, 25, and 30 min), samples were collected and followed by centrifugation for separation of the HMZCO nanozymes