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Extracellular matrix proteins secreted by embryos contribute to cellular adhesion and tissue organization processes that are essential for implantation [59, 417]

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35 The evolutionarily conserved, ~90-residue-long PDZ sequence allows the scaffolding proteins to perform two major functions: 1) anchoring the intracellular C-terminus of transmembrane proteins (TJs, ion channels, receptors, etc.) and 2) establishing scaffolding networks via interactions with other PDZ proteins through PDZPDZ dimerization

(B) The ATP7B protein, known as ATPase copper-transporting beta, contains a phosphatase domain, a phosphorylation domain, an ATP binding domain, a metal binding domain, and eight transmembrane segments

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