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In a 12-month clinical trial that was randomized and double-blinded, involving 60 postmenopausal women, the concurrent administration of curcumin at a dosage of 110 mg daily and alendronate at 5 mg daily was observed to notably enhance BMD and more effectively diminish the levels of bone resorption markers compared to the use of either drug alone (Khanizadeh et al., 2018)

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If autophagy is insufficient to remove excess ROS, it may cause the death of tumor cells