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However, differences in INS activity in pancreatic islets have also been linked to these genetic polymorphisms, as well as effects on beta-cell function and resilience ( Eizirik et al
However, immunoassays for measurement of 8-OHdG and F2-isoP have been criticized, although results employing this technology being widely published
Early animal and small human studies suggest it is generally well tolerated in the short term, but we do not yet have large, longterm trials
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