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GPs can prescribe B12 injections following appropriate investigation, which should include: Full blood count to identify macrocytic anaemia Serum B12 and folate levels to confirm deficiency (using laboratory-specific reference ranges) Methylmalonic acid and/or homocysteine when B12 results are borderline Intrinsic factor antibodies if pernicious anaemia is suspected Additional tests depending on clinical presentation (e.g., thyroid function, coeliac serology) When both B12 and folate deficiency are present, B12 should be replaced before folate to avoid precipitating subacute combined degeneration of the spinal cord

Avoid if pregnant, breastfeeding, or planning pregnancy

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This change was accompanied by a decrease in thyroid calcitonin expression

Endocrine disrupting chemicals: exposure, effects on human health, mechanisms of action, models for testing and strategies for prevention

That kind of bone-deep fatigue that follows you around its the worst, isnt it