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Vimpat should be used with caution in patients with underlying proarrhythmic conditions such as known cardiac conduction problems (e.g., marked first-degree AV block, second-degree or higher AV block, and sick sinus syndrome without pacemaker), severe cardiac disease (such as myocardial ischemia or heart failure, or structural heart disease), and cardiac sodium channelopathies (e.g., Brugada Syndrome)

Use Sterile Equipment, Every Time: This is a big one

doi: 10.1016/s0168-8278(97)80361-3

E., Hwang S

These latter mRNA methylation events represent important posttranscriptional mechanisms for the regulation of gene expression

There are certain medical conditions and risk factors that make it unsafe