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A 2025 review by Jozwiak and colleagues surveys the peptides multifunctionality and possible medical applications (PMC11859134), and is a useful map of what has and has not been established

Bold values indicate the best result in each column

There is an increased interest and potential in this exciting area of research, and the future looks bright for nasal inhalation delivery for CNS and brain therapeutic applications, hand in hand with the development of peptides as drug candidates, to be delivered intranasally

This has positioned it as a compound of interest in models investigating combinatorial peptide therapies targeting multiple pathways involved in energy homeostasis

1.62.3% with placebo at 52 weeks 38