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The depletion of NADPH results in increased oxidative stress within the cell as it is a required cofactor in the production of GSH, and this oxidative stress can result in DNA damage

Liver pathology in infantile mitochondrial DNA depletion syndrome
1 , a001651 (2009)

Targeting YAP activity and glutamine metabolism cooperatively suppresses tumor progression by preventing extracellular matrix accumulation

Surdosage dacide folique : risques et prvention Surdosage de mlatonine : quels effets secondaires

Novel p53 Mutant Mouse Model Recapitulates the Biology of Human Therapy-Related Myeloid Neoplasms