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There is evidence that ACTH can inhibit CRH synthesis in the context of elevated CRH levels due to Addisons disease or hypopituitarism, although not in the context of normal human subjects (215)

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IV therapy can benefit people with diabetes and may be needed to ensure diabetic patients remain in good health

Schoenmakers, Peter

Vollbracht et al

CH can act as a preleukemic reservoir, particularly in older individuals, and its expansion is often triggered by cancer treatments like chemoradiation and CAR-T therapy