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The host immune responses to helminths include a strong Th2 immune response, Treg response, and the production of regulatory cytokines, such as IL-10 [73-81]

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Therefore, the relatively low abundance of lipoylation in untreated cells suggests that lipoylation is rate-limiting for the OGDHc, and our findings are consistent with the accumulation of Lp glu following ABHD11 inhibition, which reduces OGDHc activity (Fig