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This breeding resulted in Cre-carrying homozygous IGF-1R floxed mice ( rod Igf-1r / ) and homozygous IGF-1R floxed mice (wild-type control)

Hoboken, NJ: John Wiley & Sons Ltd

Thats because the condition affects mostly women, and it often begins or worsens at puberty, during pregnancy, following gynecologic surgery, and around the time of menopause

[DOI] [PubMed] [Google Scholar] 52.Schrauzer G.N., Deutsch E., Windgassen R.J
In: Oxidative stress: diagnostics, prevention, and therapy