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Author contributions XL: Conceptualization, Visualization, Writingoriginal draft

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Garcia-Fernandez M, Sierra I, Puche JE, Guerra L, Castilla-Cortazar I

A note on why the concentration choice matters beyond convenience: a higher-concentration build (10 mg/mL) keeps every draw comfortably inside one barrel across the whole ladder, but leaves less margin for a small measurement slip, since each unit carries more drug

4 We then discuss the trafficking of metals to downstream metalloenzyme targets, contextualizing this discussion around the concept of a metallochaperone, focusing first on the biogenesis or maturation of metallocofactors in specific enzymes, followed by moving metals across a membrane

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