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Mechanistically, IgG-autoantibodies induced an enhanced nuclear translocation of the transcription factor cAMP response element modulator (CREM) and its binding to the GPX4 promoter

Ind J Clin Biochem 25:225243 [DOI] [PMC free article] [PubMed] [Google Scholar] Singh M, Kaur M, Silakari O (2014) Flavones: an important scaffold for medicinal chemistry

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In addition to acting as the major intracellular activator of artemisinins, ferrous heme is the primary source of oxidative stress during the blood stage of P

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The medical community now recognizes melasma as a condition with chronic inflammatory characteristics, requiring a multi-layered treatment approach that addresses both internal and external factors at various skin depths