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Here, we hypothesize that GGCT, a potential endogenous source of cysteine other than xCT-mediated cystine uptake, may contribute to resistance to therapies involving xCT inhibition, such as erastin

From the mid-forties onwards, the body produces progressively less glutathione

Quercetin affects glutathione levels and redox ratio in human aortic endothelial cells not through oxidation but formation and cellular export of quercetin-glutathione conjugates and upregulation of glutamate-cysteine ligase

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