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Compared with non-smokers, primary ATII cells from patients with COPD exhibited diverse structural changes, such as reduced mitochondrial area and perimeter, and impaired mitochondrial cristae arrangement

Hypomethylation of the PPAR gene, involved in lipid metabolism, increases its expression and stimulates steatosis development [338]

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Several assays have been developed to assess overall antioxidant activity or reducing potential as an indicator of an organisms ability to resist free radical-induced stress

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