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There is a global need to identify new ways to maximize the well-being of individuals with SCD, and nutritional interventions could possibly play a pivotal role

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Efferocytosis of apoptotic cells is well documented to create an immunosuppressive and inflammation-resolving microenvironment, reprogramming macrophages [239, 240]

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This propionyl-CoA conversion pathway is also required for the metabolism of the amino acids valine, isoleucine, and threonine and fatty acids with an odd number of carbon atoms