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Life 12(2):224 Sherman W, Beard HS, Farid R (2006) Use of an induced fit receptor structure in virtual screening

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2008 Jan-Feb;74(1):118-24

In the study of endometrial cancer (EC), we found that Brusatol sensitizes the cancer to progestins by inhibiting the NRF2-TET1-AKR1C1 pathway, which reduces AKR1C1 expression and decreases progesterone metabolism [110]

This review comprehensively examines the major epigenetic mechanisms involved in the pathogenesis and progression of various diseases

10.2165/00023210-200317060-00006 194 NagaokaT.HeinT
