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It promotes neuroplasticity in brain regions like the hippocampus by increasing BDNF levels, glutamate release, and upregulating mGLU2 receptors, particularly in the hippocampus and prefrontal cortex

Predictors with near zero-variance (i.e., predictors that have one unique value or have very few unique values relative to the number of samples, or the ratio of the most frequent to the second most frequent value is large) are also allowed, although they usually have very minimal or zero contribution to the final prediction

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Minitab 17 Statistical software [Computer software] by Minitab Inc (2010)

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