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Therefore, cancer cells not only use FAO to oxidize fatty acids and to derive energy by mitochondria but they also use acetyl-CoA to endogenously synthesize fatty acids in the cytosol using NADPH as key cofactor for anabolic enzymes (Koundouros and Poulogiannis, 2020)

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Pharmaceutics , 13 (10), 1698

Urology 69 , 11811184 (2007)

In contrast, CRC exhibits low expression level of OCTN2 [28]

Mechanisms of pathophysiology TMAO exerts its pathological effects via multiple interrelated mechanisms, including inflammation, endothelial dysfunction, and increased gut permeability, as well as promoting several disease-specific pathways