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Tumor angiogenesis leads to disordered internal tumor vasculature and aggravation of hypoxia, which in turn directly promotes the transcription of drug-resistance genes such as Multi-drug Resistance Protein1 ( MDR1 ), Multi-drug Resistant Associate Protein1 ( MRP1 ), and Breast Cancer Resistance Protein ( BRCP ) 4,5

Because these are lyophilized powders reconstituted by the end user, dose accuracy depends on correct reconstitution and measurement a source of error independent of the compound

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There is no threshold under which this substance is not prohibited

Materials are not for human or veterinary use

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