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Description
Following immediate effects, symptoms displaying systemic toxicity are manifested as generalized prostration, fatigue, weakness, dizziness, loss of coordination and ataxia

Norman PH, Vaporciyan AA, Rice DC , Correa AM
It can inhibit a key step of the folate cycle (at the level of 5-methyltetrahydrofolate), leading to the accumulation of AICAR a natural analog of AMP that potently activates AMPK

This is temporary and normal

And some people feel very disconnected from that, and that has vast diagnostic and therapeutic implications

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