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10.3390/pharmaceutics15082119 97 MaggioA.FilosaA.VitranoA.AlojG.KattamisA.CeciA.et al (2011)

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Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors

Succinate drives the production of IL1, mediated by HIF1 (39) whereas citrate accumulation leads to the production of itaconate, a potent inhibitor of isocitrate lyase, which is necessary for Mtb persistence (43)

Science 293 , 16731677 (2001)

A peristaltic pump was used to continuously pump culture from the fermentor through a flow cell (Type 71-F, Starna GmbH, Pfungstadt, Germany), which was inserted into a JASCO FP-6500 spectrofluorimeter (JASCO, Oklahoma City, OK, United States) before media returned to the fermentor vessel