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Usually, damaged melanocytes are eliminated through apoptosis and senescence, but research by Ken et al suggests that MSCs depletion may occur due to ectopic differentiation and impaired renewal

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However, some patients may experience adverse reactions associated with long-term use of these treatments

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[Analysis of 59 anaphylactic death cases]

Ultimately, it emphasizes the potential of integrating toxicological knowledge into oncology to advance cancer prevention, early detection, and therapeutic innovation