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It is crucial to deeply investigate the association between cytoskeletal structure, axonal degeneration and BIPN

Nat Rev Neurosci 11:188200 Kleinau G, Pratzka J, Nurnberg D, Gruters A, Fuhrer-Sakel D, Krude H, Kohrle J, Schoneberg T, Biebermann H (2011) Differential modulation of Beta-adrenergic receptor signaling by trace amine-associated receptor 1 agonists

Because it is a naturally occurring compound involved in energy metabolism, adverse effects are rare

doi: 10.1017/S0007114515002433

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