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Interestingly, 50% of the depleted families belong to the Lactobacillales order, or lactic acid bacteria 114

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(1) Neurodevelopmental Homeostasis: In the healthy state, mitochondrial oxidative phosphorylation (Complexes IV) supports efficient ATP generation, redox stability, and formate flux from the mitochondrial folate cycle (via SHMT2, MTHFD2)

[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Vtizou M., Pitt J.M., Daillre R., Lepage P., Waldschmitt N., Flament C., Rusakiewicz S., Routy B., Roberti M.P., Duong C.P

[ 62 ] Certain circular RNAs, such as circ_0005015, circ_0081001, and circ_0000337, have the ability to enhance cancer progression by upregulating BACH1 via the mechanism of microRNA sponging as well