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In neuroendocrine prostate tumors, loss of tumor suppressor protein kinase C (PKC) / enhanced serine metabolism through mTORC1/ATF4/PHGDH axis, which leads to aberrant DNA methylation by increased one-carbon metabolic flux, ultimately leading to treatment resistance and poor prognosis [98]
Triglycerides also play a role in overall lipid balance, and markers like ApoB provide even more insight into how cholesterol particles affect artery health

Lipids are amphiphilic molecules, which means they are composed of two parts: A hydrophilic head, which possesses an high affinity for water

10.1007/BF02535354
[Google Scholar] 88.Schuhr CA, Eisenreich W, Goese M, Stohler P, Weber W, Kupfer E, Bacher A

The excess production of ROS is one of the main molecular causes that contributes to varicocele-related male infertility, in which MIR210HG and MLLT4-AS1 (hypoxia-related lncRNAs) also showed significant positive correlations with ROS and negative correlations with sperm count and motility [48]