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55 A sustained and amplified inflammatory response accelerates the release of abundant pro-inflammatory cytokines

Sierra A, Martin-Suarez S, Valcarcel-Martin R, Pascual-Brazo J, Aelvoet SA, Abiega O, et al

[DOI] [PMC free article] [PubMed] [Google Scholar] 44.Jackson S.J., Diemel L.T., Pryce G., Baker D

Furthermore, tumor necrosis factor- (TNF) and prostaglandins (PGs), released from astrocytes under traumatic events, can reactivate their calcium signaling, and can cause increased glutamate release (Bezzi et al., Reactive astrocytes are also involved in the pathogenesis of other neuronal disorders

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Of the 59 patients with information, 40 (67.80%) presented an increase or recurrence of fever and 33 of 42 patients with data (78.57%) presented chills