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The Sdhc gene encoding a subunit of the succinate dehydrogenase enzyme, important in regulating electron flow through the ETC, was significantly upregulated in the AC-like cell state model, as were several thioredoxin genes involved in critical redox reactions ( Txn1, Txn2 ) (Fig

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[DOI] [PMC free article] [PubMed] [Google Scholar] 234.Reis J., Spencer P.S

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