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Akt pathway pro-survival signaling: TrkB activation recruits PI3K phosphorylating PIP2 to PIP3

It's pretty rare to overdose on B12 since it's water-soluble, but super high doses can cause side effects

Cyanocobalamin versus Methylcobalamin Cyanocobalamin is a synthetic form of vitamin B12 found only in supplements, while methylcobalamin is a naturally occurring form that you can get through either food sources or supplements

10.1016/j.immuni.2018.04.026 40

Improves blood flow to the brain
Common side effects: B12 injections are generally very well tolerated
