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They have shown that treatment with ALC increases serum levels of other reproductive hormones, like estradiol, progesterone, LH and decreases prolactin in the usual fashion with different phases of estrous in animal [16, 17]

doi: 10.1186/s12934-017-0646-4

251260, doi:10.1111/cts.12499

As a consequence, the effects of drugs change, and patients are no longer responsive to treatment

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Side effects can include serious medical concerns, like liver disease
