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After LPL hydrolyzes TRLs, sortilin, a member of the vacuolar protein sorting 10 (or VPS10) family, facilitates the uptake of secreted LPL and transfers it to endosomes in parenchymal cells, and LPL ends up in lysosomes for degradation [50,84]

Impairment of FAO can be attributed to the reduced activity of CPTI and CPTII in the liver

In contrast, gut metabolomics provides a clear profile of the metabolites present, but is still in its infancy and therefore has several challenges 73

We report that silencing of the C/EBP transcription factor in epidermal keratinocytes results in the sensitization of keratinocytes to UVB-induced extrinsic apoptosis mediated by the activation of caspase-8 and pro-apoptotic protein Bid

As such, results may vary

[DOI] [PubMed] [Google Scholar] 442.Andersson, D