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Carboxylic acid and hydroxy reactive moieties may be blocked with base labile groups such as, without limitation, methyl, ethyl, and acetyl in the presence of amines blocked with acid labile groups such as tert-butyl carbamate or with carbamates that are both acid and base stable but hydrolytically removable

National Library of Medicine Primary regulatory Jul 1, 2026 accessed Jul 1, 2026 ClinicalTrials.gov registry search for AOD-9604 clinical trials, including the Phase 2 obesity program by Metabolic Pharmaceuticals that failed to meet primary weight loss endpoints

Ganglioside-linked terminal sialic acid moieties on murine macrophages function as attachment receptors for murine noroviruses

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Because infliximab is partly a mouse protein, it may induce an immune reaction when given to humans, especially with repeated infusions