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Plant Cell Rep 41:365376 Wang X, Wang W, Zhang R, Ma B, Ni L, Feng H, Liu C (2023a) Melatonin attenuates high glucose-induced endothelial cell pyroptosis by activating the Nrf2 pathway to inhibit NLRP3 inflammasome activation

Mechanistically, Src mediates both the transactivation of EGFR via MMP activity and the phosphorylation-dependent inactivation of PTEN, thereby sustaining PI3K/Akt signaling [55]

Excess mitochondrial ROS production, causes cellular oxidative stress, sustains mitochondrial dysfunction and ROS production and perpetuates inflammation (Chang et al., 2021)

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