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& Bootman, M

Sometime after stress, typically 5-10 minutes, the hypothalamus-pituitary-interrenal axis will have activated interrenal cells to produce cortisol that will stimulate the restoration of energy supplies, and in the long term will help reduce energy costs by downregulating non-essential processes such as immune responses and growth

Front Neurol 13:1019554 Published 2022 Nov 9

There's some data that threonate can be neuroprotective

These recommendations will have far reaching implications for how obesity is viewed, for clinical decision-making, including potential updates to treatment guidelines, and the criteria payers may apply to cover AOMs

This dynamic became a central argument for reversing the restriction